Laroche, Audrey

Heterogeneous Mechanisms of Secondary Resistance and Clonal Selection in Sarcoma during Treatment with Nutlin. [electronic resource] - PloS one 2015 - e0137794 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0137794 doi


Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Autophagy--drug effects
Cell Cycle Checkpoints--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Clone Cells--drug effects
Drug Resistance, Neoplasm--genetics
Gene Expression Profiling
Humans
Imidazoles--pharmacology
Mutation
Ploidies
Proto-Oncogene Proteins c-mdm2--metabolism
Pyrrolidines--pharmacology
Sarcoma--drug therapy
Sequence Analysis, RNA
Signal Transduction--drug effects
Tumor Suppressor Protein p53--genetics
para-Aminobenzoates--pharmacology