Sizun, Gwenaëlle

Design, synthesis and antiviral evaluation of 2'-C-methyl branched guanosine pronucleotides: the discovery of IDX184, a potent liver-targeted HCV polymerase inhibitor. [electronic resource] - Future medicinal chemistry 2015 - 1675-700 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1756-8927

10.4155/fmc.15.96 doi


Antiviral Agents--chemical synthesis
Drug Discovery
Guanosine Monophosphate--analogs & derivatives
Hepacivirus--drug effects
Hepatitis C--drug therapy
Humans
Structure-Activity Relationship