Schirris, Tom J J <br/><br/>
Mitochondrial ADP/ATP exchange inhibition: a novel off-target mechanism underlying ibipinabant-induced myotoxicity.  [electronic resource] 

 -  Scientific reports  Sep 2015 
 - 14533 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2045-2322 
<br/><br/><label>Standard No.: </label>10.1038/srep14533  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenosine Diphosphate--metabolism<br/>Adenosine Triphosphate--antagonists & inhibitors<br/>Amidines--chemical synthesis<br/>Animals<br/>Anti-Obesity Agents--chemical synthesis<br/>Cannabinoid Receptor Antagonists--chemical synthesis<br/>Cell Line<br/>Dogs<br/>Dose-Response Relationship, Drug<br/>Drug Design<br/>Electron Transport Chain Complex Proteins--antagonists & inhibitors<br/>Humans<br/>Mice<br/>Mitochondria--drug effects<br/>Mitochondrial ADP, ATP Translocases--antagonists & inhibitors<br/>Muscle, Skeletal--drug effects<br/>Myoblasts--cytology<br/>Obesity--drug therapy<br/>Oxygen Consumption--drug effects<br/>Pyrazoles--chemical synthesis<br/>Reactive Oxygen Species--agonists<br/>Receptor, Cannabinoid, CB1--antagonists & inhibitors<br/>Structure-Activity Relationship