TY - GEN AU - Papayannidis,C AU - DeAngelo,D J AU - Stock,W AU - Huang,B AU - Shaik,M N AU - Cesari,R AU - Zheng,X AU - Reynolds,J M AU - English,P A AU - Ozeck,M AU - Aster,J C AU - Kuo,F AU - Huang,D AU - Lira,P D AU - McLachlan,K R AU - Kern,K A AU - Garcia-Manero,G AU - Martinelli,G TI - A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma SN - 2044-5385 PY - 2016///0125 KW - Adolescent KW - Adult KW - Antineoplastic Agents KW - pharmacokinetics KW - Female KW - High-Throughput Nucleotide Sequencing KW - Humans KW - Male KW - Precursor T-Cell Lymphoblastic Leukemia-Lymphoma KW - drug therapy KW - Receptor, Notch1 KW - genetics KW - Tetrahydronaphthalenes KW - therapeutic use KW - Valine KW - analogs & derivatives KW - Young Adult N1 - Publication Type: Clinical Trial, Phase I; Letter; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/bcj.2015.80 ER -