TY  - GEN
AU  - Gong,Xuezhong
AU  - Ivanov,Vladimir N
AU  - Hei,Tom K
TI  - 2,3,5,6-Tetramethylpyrazine (TMP) down-regulated arsenic-induced heme oxygenase-1 and ARS2 expression by inhibiting Nrf2, NF-κB, AP-1 and MAPK pathways in human proximal tubular cells
SN  - 1432-0738
PY  - 2017///0309
KW  - Antioxidants
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Arsenites
KW  - toxicity
KW  - Cell Line
KW  - Cytoprotection
KW  - Dose-Response Relationship, Drug
KW  - Down-Regulation
KW  - Enzyme Inhibitors
KW  - Heme Oxygenase-1
KW  - antagonists & inhibitors
KW  - Humans
KW  - Kidney Tubules, Proximal
KW  - Mitochondria
KW  - Mitogen-Activated Protein Kinases
KW  - metabolism
KW  - NF-E2-Related Factor 2
KW  - NF-kappa B
KW  - Nuclear Proteins
KW  - Oxidative Stress
KW  - Pyrazines
KW  - Reactive Oxygen Species
KW  - Signal Transduction
KW  - Sodium Compounds
KW  - Time Factors
KW  - Transcription Factor AP-1
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1007/s00204-015-1600-z
ER  -