LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner. [electronic resource]
- Nucleic acids research Jan 2016
- 582-94 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1362-4962
10.1093/nar/gkv948 doi
Binding Sites Cell Proliferation--genetics Chromatin Assembly and Disassembly Cyclin-Dependent Kinase Inhibitor p21--genetics Gene Deletion Gene Expression Regulation, Neoplastic HCT116 Cells HT29 Cells Humans Mutation Organ Specificity Phosphorylation Promoter Regions, Genetic Protein Binding RNA, Small Interfering--genetics Receptors, Cytoplasmic and Nuclear--genetics Signal Transduction Tumor Suppressor Protein p53--antagonists & inhibitors