Raheem, Izzat T <br/><br/>
Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors.  [electronic resource] 

 -  Journal of medicinal chemistry  Oct 2015 
 - 8154-65 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.5b01037  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Area Under Curve<br/>Dogs<br/>Dose-Response Relationship, Drug<br/>Drug Design<br/>HIV Integrase--drug effects<br/>HIV Integrase Inhibitors--chemical synthesis<br/>HIV-1--drug effects<br/>Humans<br/>Models, Molecular<br/>Prodrugs<br/>Pyridones--chemical synthesis<br/>Rats