Tris(2-chloroethyl)phosphate-induced cell growth arrest via attenuation of SIRT1-independent PI3K/Akt/mTOR pathway. [electronic resource]
- Journal of applied toxicology : JAT 07 2016
- 914-24 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1099-1263
10.1002/jat.3223 doi
Cell Line Cell Proliferation--drug effects Cell Survival--drug effects Flame Retardants--toxicity Hep G2 Cells Humans Liver--cytology Organophosphates--toxicity Oxidation-Reduction Phosphatidylinositol 3-Kinases--genetics Plasticizers--toxicity Proto-Oncogene Proteins c-akt--genetics RNA, Messenger--genetics Reactive Oxygen Species--metabolism Signal Transduction Sirtuin 1--genetics TOR Serine-Threonine Kinases--genetics Up-Regulation