Gao, Yu

Differential IKK/NF-κB Activity Is Mediated by TSC2 through mTORC1 in PTEN-Null Prostate Cancer and Tuberous Sclerosis Complex Tumor Cells. [electronic resource] - Molecular cancer research : MCR Dec 2015 - 1602-14 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1557-3125

10.1158/1541-7786.MCR-15-0213 doi


Cell Line, Tumor
Gene Expression Regulation, Neoplastic
HeLa Cells
Humans
I-kappa B Kinase--metabolism
Male
Mechanistic Target of Rapamycin Complex 1
Multiprotein Complexes--metabolism
Mutation
NF-kappa B--metabolism
PTEN Phosphohydrolase--deficiency
Prostatic Neoplasms--genetics
Signal Transduction
TOR Serine-Threonine Kinases--metabolism
Tuberous Sclerosis--genetics
Tuberous Sclerosis Complex 2 Protein
Tumor Suppressor Proteins--genetics