Differential IKK/NF-κB Activity Is Mediated by TSC2 through mTORC1 in PTEN-Null Prostate Cancer and Tuberous Sclerosis Complex Tumor Cells. [electronic resource]
- Molecular cancer research : MCR Dec 2015
- 1602-14 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1557-3125
10.1158/1541-7786.MCR-15-0213 doi
Cell Line, Tumor Gene Expression Regulation, Neoplastic HeLa Cells Humans I-kappa B Kinase--metabolism Male Mechanistic Target of Rapamycin Complex 1 Multiprotein Complexes--metabolism Mutation NF-kappa B--metabolism PTEN Phosphohydrolase--deficiency Prostatic Neoplasms--genetics Signal Transduction TOR Serine-Threonine Kinases--metabolism Tuberous Sclerosis--genetics Tuberous Sclerosis Complex 2 Protein Tumor Suppressor Proteins--genetics