TY - GEN AU - LaCuran,Alecander E AU - Pegg,Kevin M AU - Liu,Eleanor M AU - Bethel,Christopher R AU - Ai,Ni AU - Welsh,William J AU - Bonomo,Robert A AU - Oelschlaeger,Peter TI - Elucidating the Role of Residue 67 in IMP-Type Metallo-β-Lactamase Evolution SN - 1098-6596 PY - 2016///0831 KW - Amino Acid Substitution KW - Catalytic Domain KW - Escherichia coli KW - enzymology KW - Evolution, Molecular KW - Gene Expression KW - Hydrolysis KW - Kinetics KW - Microbial Sensitivity Tests KW - Molecular Docking Simulation KW - Mutation KW - Phenylalanine KW - chemistry KW - Protein Structure, Secondary KW - Recombinant Proteins KW - Structure-Activity Relationship KW - Substrate Specificity KW - Valine KW - beta-Lactamases KW - beta-Lactams N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1128/AAC.01651-15 ER -