TY  - GEN
AU  - Prahallad,Anirudh
AU  - Heynen,Guus J J E
AU  - Germano,Giovanni
AU  - Willems,Stefan M
AU  - Evers,Bastiaan
AU  - Vecchione,Loredana
AU  - Gambino,Valentina
AU  - Lieftink,Cor
AU  - Beijersbergen,Roderick L
AU  - Di Nicolantonio,Federica
AU  - Bardelli,Alberto
AU  - Bernards,Rene
TI  - PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs
SN  - 2211-1247
PY  - 2016///0706
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Cell Line, Tumor
KW  - Colonic Neoplasms
KW  - drug therapy
KW  - Drug Resistance, Neoplasm
KW  - drug effects
KW  - ErbB Receptors
KW  - genetics
KW  - Gene Expression Regulation, Neoplastic
KW  - Genetic Vectors
KW  - Genomic Library
KW  - High-Throughput Nucleotide Sequencing
KW  - Humans
KW  - Indoles
KW  - Lentivirus
KW  - MAP Kinase Signaling System
KW  - Melanoma
KW  - Mice
KW  - Mice, Inbred NOD
KW  - Protein Tyrosine Phosphatase, Non-Receptor Type 11
KW  - antagonists & inhibitors
KW  - Proto-Oncogene Proteins B-raf
KW  - RNA, Small Interfering
KW  - Sulfonamides
KW  - Transduction, Genetic
KW  - Vemurafenib
KW  - Xenograft Model Antitumor Assays
KW  - ras Proteins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.celrep.2015.08.037
ER  -