Prahallad, Anirudh
PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs. [electronic resource]
- Cell reports Sep 2015
- 1978-85 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ISSN: 2211-1247
Standard No.: 10.1016/j.celrep.2015.08.037 doi
Subjects--Topical Terms: Animals Antineoplastic Agents--pharmacology Cell Line, Tumor Colonic Neoplasms--drug therapy Drug Resistance, Neoplasm--drug effects ErbB Receptors--genetics Gene Expression Regulation, Neoplastic Genetic Vectors Genomic Library High-Throughput Nucleotide Sequencing Humans Indoles--pharmacology Lentivirus--genetics MAP Kinase Signaling System Melanoma--drug therapy Mice Mice, Inbred NOD Protein Tyrosine Phosphatase, Non-Receptor Type 11--antagonists & inhibitors Proto-Oncogene Proteins B-raf--genetics RNA, Small Interfering--genetics Sulfonamides--pharmacology Transduction, Genetic Vemurafenib Xenograft Model Antitumor Assays ras Proteins--genetics