TY - GEN AU - Singleton,Katherine R AU - Hinz,Trista K AU - Kleczko,Emily K AU - Marek,Lindsay A AU - Kwak,Jeff AU - Harp,Taylor AU - Kim,Jihye AU - Tan,Aik Choon AU - Heasley,Lynn E TI - Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC SN - 1538-7445 PY - 2016///0209 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Benzamides KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Cell Line, Tumor KW - Disease Models, Animal KW - Drug Resistance, Neoplasm KW - Drug Synergism KW - Gene Library KW - Genes, Essential KW - Genomics KW - methods KW - Humans KW - Lung Neoplasms KW - Morpholines KW - Piperazines KW - Protein Binding KW - Protein Kinase Inhibitors KW - Pyrazoles KW - Pyrimidines KW - RNA Interference KW - RNA, Small Interfering KW - genetics KW - Receptor, Fibroblast Growth Factor, Type 1 KW - antagonists & inhibitors KW - Signal Transduction KW - drug effects KW - TOR Serine-Threonine Kinases KW - Tumor Burden KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1158/0008-5472.CAN-15-0509 ER -