Kakeya, Hideaki <br/><br/>
RQN-18690A (18-deoxyherboxidiene) targets SF3b, a spliceosome component, and inhibits angiogenesis.  [electronic resource] 

 -  The Journal of antibiotics  Feb 2016 
 - 121-3 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1881-1469 
<br/><br/><label>Standard No.: </label>10.1038/ja.2015.94  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Cells, Cultured<br/>Enzyme Inhibitors--pharmacology<br/>Fatty Alcohols--pharmacology<br/>Human Umbilical Vein Endothelial Cells--drug effects<br/>Humans<br/>Models, Molecular<br/>Molecular Structure<br/>Neovascularization, Physiologic--drug effects<br/>Phosphoproteins--antagonists & inhibitors<br/>Pyrans--pharmacology<br/>RNA Splicing Factors<br/>Ribonucleoprotein, U2 Small Nuclear--antagonists & inhibitors<br/>Spliceosomes--drug effects