TY - GEN AU - Mu,Xueru AU - Español-Suñer,Regina AU - Mederacke,Ingmar AU - Affò,Silvia AU - Manco,Rita AU - Sempoux,Christine AU - Lemaigre,Frédéric P AU - Adili,Arlind AU - Yuan,Detian AU - Weber,Achim AU - Unger,Kristian AU - Heikenwälder,Mathias AU - Leclercq,Isabelle A AU - Schwabe,Robert F TI - Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment SN - 1558-8238 PY - 2016///0115 KW - Animals KW - Bile Ducts KW - cytology KW - Biomarkers, Tumor KW - analysis KW - Carbon Tetrachloride KW - toxicity KW - Carcinogens KW - Cell Dedifferentiation KW - Cell Lineage KW - Cocarcinogenesis KW - Comparative Genomic Hybridization KW - Diethylnitrosamine KW - Gene Expression Profiling KW - Genes, Reporter KW - Hepatocytes KW - chemistry KW - Keratin-19 KW - Liver Cirrhosis, Experimental KW - pathology KW - Liver Neoplasms, Experimental KW - chemically induced KW - Male KW - Mice KW - Mice, Transgenic KW - Microfilament Proteins KW - Neoplastic Stem Cells KW - Osteopontin KW - PTEN Phosphohydrolase KW - deficiency KW - Precancerous Conditions KW - Tamoxifen KW - pharmacology KW - alpha-Fetoproteins N1 - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/JCI77995 ER -