TY - GEN AU - Hosaka,Shinya AU - Murayama,Norie AU - Satsukawa,Masahiro AU - Uehara,Shotaro AU - Shimizu,Makiko AU - Iwasaki,Kazuhide AU - Iwano,Shunsuke AU - Uno,Yasuhiro AU - Yamazaki,Hiroshi TI - Similar substrate specificity of cynomolgus monkey cytochrome P450 2C19 to reported human P450 2C counterpart enzymes by evaluation of 89 drug clearances SN - 1099-081X PY - 2016///1014 KW - Animals KW - Biotransformation KW - Chromatography, High Pressure Liquid KW - Chromatography, Reverse-Phase KW - Cytochrome P-450 CYP2C19 KW - genetics KW - Cytochrome P-450 CYP2C9 KW - Histamine H1 Antagonists, Non-Sedating KW - chemistry KW - Humans KW - Isoenzymes KW - Loratadine KW - analogs & derivatives KW - Macaca fascicularis KW - metabolism KW - Molecular Structure KW - Oxidation-Reduction KW - Recombinant Proteins KW - Spectrometry, Mass, Electrospray Ionization KW - Substrate Specificity KW - Tandem Mass Spectrometry KW - Xenobiotics N1 - Publication Type: Journal Article UR - https://doi.org/10.1002/bdd.1991 ER -