Modification of paclitaxel-loaded solid lipid nanoparticles with 2-hydroxypropyl-β-cyclodextrin enhances absorption and reduces nephrotoxicity associated with intravenous injection. [electronic resource]
- International journal of nanomedicine 2015
- 5397-405 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1178-2013
10.2147/IJN.S86474 doi
2-Hydroxypropyl-beta-cyclodextrin Albumins--chemistry Animals Antineoplastic Agents--chemistry Apoptosis Area Under Curve Breast Neoplasms Cell Proliferation Cell Survival Creatinine--blood Drug Carriers--pharmacokinetics Drug Screening Assays, Antitumor Female Flow Cytometry Humans Injections, Intravenous Kidney--drug effects Lipids--chemistry MCF-7 Cells Male Mice Mice, Inbred BALB C Microscopy, Confocal Nanoparticles--chemistry Neoplasm Transplantation Paclitaxel--chemistry Rats beta-Cyclodextrins--chemistry