Temporal pharmacokinetic/pharmacodynamic interaction between human CD3ε antigen-targeted monoclonal antibody otelixizumab and CD3ε binding and expression in human peripheral blood mononuclear cell static culture. [electronic resource]
- The Journal of pharmacology and experimental therapeutics Nov 2015
- 199-205 p. digital
Publication Type: Journal Article
1521-0103
10.1124/jpet.115.224899 doi
Antibodies, Monoclonal, Humanized--pharmacokinetics CD3 Complex--blood Cells, Cultured Humans Leukocytes, Mononuclear--drug effects Protein Binding Receptors, Antigen, T-Cell--metabolism Time Factors