TY  - GEN
AU  - Reese,Melinda J
AU  - Bowers,Gary D
AU  - Humphreys,Joan E
AU  - Gould,Elizabeth P
AU  - Ford,Susan L
AU  - Webster,Lindsey O
AU  - Polli,Joseph W
TI  - Drug interaction profile of the HIV integrase inhibitor cabotegravir: assessment from in vitro studies and a clinical investigation with midazolam
SN  - 1366-5928
PY  - 2016///1107
KW  - ATP-Binding Cassette Transporters
KW  - metabolism
KW  - Administration, Oral
KW  - Adolescent
KW  - Adult
KW  - Aged
KW  - Animals
KW  - Anti-HIV Agents
KW  - administration & dosage
KW  - Area Under Curve
KW  - Cytochrome P-450 CYP3A
KW  - chemistry
KW  - Dogs
KW  - Dose-Response Relationship, Drug
KW  - Drug Interactions
KW  - Female
KW  - HIV Infections
KW  - drug therapy
KW  - HIV Integrase Inhibitors
KW  - Hepatocytes
KW  - drug effects
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Madin Darby Canine Kidney Cells
KW  - Male
KW  - Midazolam
KW  - Middle Aged
KW  - Organic Anion Transport Protein 1
KW  - antagonists & inhibitors
KW  - Organic Anion Transporters
KW  - Organic Anion Transporters, Sodium-Independent
KW  - Pyridones
KW  - Young Adult
N1  - Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.3109/00498254.2015.1081993
ER  -