TY - GEN AU - Xiao,Qingli AU - Yan,Ping AU - Ma,Xiucui AU - Liu,Haiyan AU - Perez,Ronaldo AU - Zhu,Alec AU - Gonzales,Ernesto AU - Tripoli,Danielle L AU - Czerniewski,Leah AU - Ballabio,Andrea AU - Cirrito,John R AU - Diwan,Abhinav AU - Lee,Jin-Moo TI - Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis SN - 1529-2401 PY - 2015///1125 KW - Amyloid beta-Peptides KW - genetics KW - Amyloid beta-Protein Precursor KW - Animals KW - Basic Helix-Loop-Helix Leucine Zipper Transcription Factors KW - Brain KW - pathology KW - Calcium-Binding Proteins KW - metabolism KW - Cell Line, Tumor KW - Dependovirus KW - Disease Models, Animal KW - Gene Expression Regulation KW - Glial Fibrillary Acidic Protein KW - Green Fluorescent Proteins KW - Lysosomes KW - Mice KW - Mice, Transgenic KW - Microfilament Proteins KW - Mutation KW - Neuroblastoma KW - Neurons KW - Plaque, Amyloid KW - Presenilin-1 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1523/JNEUROSCI.0705-15.2015 ER -