TY - GEN AU - Advani,Sunil J AU - Camargo,Maria Fernanda AU - Seguin,Laetitia AU - Mielgo,Ainhoa AU - Anand,Sudarshan AU - Hicks,Angel M AU - Aguilera,Joseph AU - Franovic,Aleksandra AU - Weis,Sara M AU - Cheresh,David A TI - Kinase-independent role for CRAF-driving tumour radioresistance via CHK2 SN - 2041-1723 PY - 2016///0420 KW - Animals KW - Cell Line, Tumor KW - Checkpoint Kinase 2 KW - metabolism KW - DNA Damage KW - genetics KW - Fluorescent Antibody Technique KW - HCT116 Cells KW - Humans KW - Immunoblotting KW - Immunoprecipitation KW - Mice KW - Mutation KW - Neoplasm Transplantation KW - Phosphorylation KW - radiation effects KW - Proto-Oncogene Proteins B-raf KW - Proto-Oncogene Proteins c-raf KW - Radiation Tolerance KW - Radiation, Ionizing KW - Serine KW - Xenograft Model Antitumor Assays KW - p21-Activated Kinases N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/ncomms9154 ER -