TY  - GEN
AU  - Song,Tuzz-Ying
AU  - Yeh,Shu-Lan
AU  - Hu,Miao-Lin
AU  - Chen,Mei-Yau
AU  - Yang,Nae-Cherng
TI  - A Nampt inhibitor FK866 mimics vitamin B3 deficiency by causing senescence of human fibroblastic Hs68 cells via attenuation of NAD(+)-SIRT1 signaling
SN  - 1573-6768
PY  - 2016///0801
KW  - AMP-Activated Protein Kinases
KW  - metabolism
KW  - Acrylamides
KW  - pharmacology
KW  - Cell Line
KW  - Cell Proliferation
KW  - drug effects
KW  - Cellular Senescence
KW  - Cytokines
KW  - antagonists & inhibitors
KW  - Enzyme Inhibitors
KW  - Fibroblasts
KW  - cytology
KW  - Glutathione
KW  - Humans
KW  - NAD
KW  - NADP
KW  - Niacin
KW  - Niacinamide
KW  - deficiency
KW  - Nicotinamide Phosphoribosyltransferase
KW  - Piperidines
KW  - Signal Transduction
KW  - Sirtuin 1
KW  - TOR Serine-Threonine Kinases
KW  - Tumor Suppressor Protein p53
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s10522-015-9605-9
ER  -