Song, Tuzz-Ying <br/><br/>
A Nampt inhibitor FK866 mimics vitamin B3 deficiency by causing senescence of human fibroblastic Hs68 cells via attenuation of NAD(+)-SIRT1 signaling.  [electronic resource] 

 -  Biogerontology  Dec 2015 
 - 789-800 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1573-6768 
<br/><br/><label>Standard No.: </label>10.1007/s10522-015-9605-9  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>AMP-Activated Protein Kinases--metabolism<br/>Acrylamides--pharmacology<br/>Cell Line<br/>Cell Proliferation--drug effects<br/>Cellular Senescence--drug effects<br/>Cytokines--antagonists & inhibitors<br/>Enzyme Inhibitors--pharmacology<br/>Fibroblasts--cytology<br/>Glutathione--metabolism<br/>Humans<br/>NAD--metabolism<br/>NADP--metabolism<br/>Niacin--pharmacology<br/>Niacinamide--deficiency<br/>Nicotinamide Phosphoribosyltransferase--antagonists & inhibitors<br/>Piperidines--pharmacology<br/>Signal Transduction--drug effects<br/>Sirtuin 1--metabolism<br/>TOR Serine-Threonine Kinases--metabolism<br/>Tumor Suppressor Protein p53--metabolism