Chuang, Huai-Yao

Toward reducing immunogenicity of enzyme replacement therapy: altering the specificity of human β-glucuronidase to compensate for α-iduronidase deficiency. [electronic resource] - Protein engineering, design & selection : PEDS Nov 2015 - 519-29 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1741-0134

10.1093/protein/gzv041 doi


Amino Acid Sequence
Enzyme Replacement Therapy--adverse effects
Glucuronidase--chemistry
HEK293 Cells
Humans
Iduronidase--deficiency
Models, Molecular
Mucopolysaccharidoses
Protein Engineering