TY - GEN AU - Charlier,E AU - Malaise,O AU - Zeddou,M AU - Neuville,S AU - Cobraiville,G AU - Deroyer,C AU - Sanchez,C AU - Gillet,P AU - Kurth,W AU - de Seny,D AU - Relic,B AU - Malaise,M G TI - Restriction of spontaneous and prednisolone-induced leptin production to dedifferentiated state in human hip OA chondrocytes: role of Smad1 and β-catenin activation SN - 1522-9653 PY - 2016///1017 KW - Activin Receptors, Type II KW - drug effects KW - Adult KW - Aged KW - Aged, 80 and over KW - Cartilage, Articular KW - cytology KW - Cell Dedifferentiation KW - Chondrocytes KW - Collagen Type X KW - Core Binding Factor Alpha 1 Subunit KW - Female KW - Glucocorticoids KW - pharmacology KW - Glycogen Synthase Kinase 3 KW - Humans KW - In Vitro Techniques KW - Leptin KW - metabolism KW - Lymphotoxin-alpha KW - Male KW - Matrix Metalloproteinase 13 KW - Middle Aged KW - Osteoarthritis, Hip KW - genetics KW - Prednisolone KW - Protein Serine-Threonine Kinases KW - RNA, Messenger KW - Receptor, Transforming Growth Factor-beta Type I KW - Receptors, Transforming Growth Factor beta KW - SOX9 Transcription Factor KW - Smad1 Protein KW - Smad2 Protein KW - Smad5 Protein KW - Wnt Signaling Pathway KW - beta Catenin N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.joca.2015.08.002 ER -