Charlier, E <br/><br/>
Restriction of spontaneous and prednisolone-induced leptin production to dedifferentiated state in human hip OA chondrocytes: role of Smad1 and β-catenin activation.  [electronic resource] 

 -  Osteoarthritis and cartilage  Feb 2016 
 - 315-24 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1522-9653 
<br/><br/><label>Standard No.: </label>10.1016/j.joca.2015.08.002  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Activin Receptors, Type II--drug effects<br/>Adult<br/>Aged<br/>Aged, 80 and over<br/>Cartilage, Articular--cytology<br/>Cell Dedifferentiation--drug effects<br/>Chondrocytes--drug effects<br/>Collagen Type X--drug effects<br/>Core Binding Factor Alpha 1 Subunit--drug effects<br/>Female<br/>Glucocorticoids--pharmacology<br/>Glycogen Synthase Kinase 3--drug effects<br/>Humans<br/>In Vitro Techniques<br/>Leptin--metabolism<br/>Lymphotoxin-alpha--drug effects<br/>Male<br/>Matrix Metalloproteinase 13--drug effects<br/>Middle Aged<br/>Osteoarthritis, Hip--genetics<br/>Prednisolone--pharmacology<br/>Protein Serine-Threonine Kinases--drug effects<br/>RNA, Messenger--drug effects<br/>Receptor, Transforming Growth Factor-beta Type I<br/>Receptors, Transforming Growth Factor beta--drug effects<br/>SOX9 Transcription Factor--drug effects<br/>Smad1 Protein--drug effects<br/>Smad2 Protein--drug effects<br/>Smad5 Protein--drug effects<br/>Wnt Signaling Pathway--drug effects<br/>beta Catenin--drug effects