TY - GEN AU - Jiang,Xiaojun AU - Pissaloux,Daniel AU - De La Fouchardiere,Christelle AU - Desseigne,Françoise AU - Wang,Qing AU - Attignon,Valery AU - Fondrevelle,Marie-Eve AU - De La Fouchardiere,Arnaud AU - Perol,Maurice AU - Cassier,Philippe AU - Seigne,Christelle AU - Perol,David AU - Ray-Coquard,Isabelle AU - Meeus,Pierre AU - Fayette,Jerome AU - Flechon,Aude AU - Le Cesne,Axel AU - Penel,Nicolas AU - Tredan,Olivier AU - Blay,Jean-Yves TI - The sum of gains and losses of genes encoding the protein tyrosine kinase targets predicts response to multi-kinase inhibitor treatment: Characterization, validation, and prognostic value SN - 1949-2553 PY - 2016///0722 KW - Adult KW - Aged KW - Algorithms KW - Antineoplastic Agents KW - therapeutic use KW - Biomarkers, Tumor KW - antagonists & inhibitors KW - DNA Copy Number Variations KW - Decision Support Techniques KW - Disease-Free Survival KW - Female KW - Gene Amplification KW - Gene Deletion KW - Gene Expression Profiling KW - Genetic Testing KW - methods KW - Humans KW - Kaplan-Meier Estimate KW - Male KW - Middle Aged KW - Molecular Targeted Therapy KW - Neoplasms KW - drug therapy KW - Patient Selection KW - Precision Medicine KW - Predictive Value of Tests KW - Protein Kinase Inhibitors KW - Protein-Tyrosine Kinases KW - Reproducibility of Results KW - Risk Factors KW - Signal Transduction KW - Time Factors KW - Treatment Outcome KW - Young Adult N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.18632/oncotarget.4557 ER -