TY - GEN AU - Bailon-Moscoso,Natalia AU - González-Arévalo,Gabriela AU - Velásquez-Rojas,Gabriela AU - Malagon,Omar AU - Vidari,Giovanni AU - Zentella-Dehesa,Alejandro AU - Ratovitski,Edward A AU - Ostrosky-Wegman,Patricia TI - Phytometabolite Dehydroleucodine Induces Cell Cycle Arrest, Apoptosis, and DNA Damage in Human Astrocytoma Cells through p73/p53 Regulation SN - 1932-6203 PY - 2016///0614 KW - Antineoplastic Agents, Phytogenic KW - pharmacology KW - Apoptosis KW - drug effects KW - Astrocytoma KW - drug therapy KW - Cell Cycle Checkpoints KW - Cell Line, Tumor KW - Cell Proliferation KW - Cell Survival KW - Cyclin-Dependent Kinase Inhibitor p21 KW - biosynthesis KW - DNA Damage KW - DNA-Binding Proteins KW - metabolism KW - Histones KW - Humans KW - Lactones KW - Nuclear Proteins KW - Phosphorylation KW - Secondary Metabolism KW - Sesquiterpenes KW - Tumor Protein p73 KW - Tumor Suppressor Protein p53 KW - Tumor Suppressor Proteins KW - bcl-2-Associated X Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0136527 ER -