TY - GEN AU - Hrustanovic,Gorjan AU - Olivas,Victor AU - Pazarentzos,Evangelos AU - Tulpule,Asmin AU - Asthana,Saurabh AU - Blakely,Collin M AU - Okimoto,Ross A AU - Lin,Luping AU - Neel,Dana S AU - Sabnis,Amit AU - Flanagan,Jennifer AU - Chan,Elton AU - Varella-Garcia,Marileila AU - Aisner,Dara L AU - Vaishnavi,Aria AU - Ou,Sai-Hong I AU - Collisson,Eric A AU - Ichihara,Eiki AU - Mack,Philip C AU - Lovly,Christine M AU - Karachaliou,Niki AU - Rosell,Rafael AU - Riess,Jonathan W AU - Doebele,Robert C AU - Bivona,Trever G TI - RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer SN - 1546-170X PY - 2015///1208 KW - Anaplastic Lymphoma Kinase KW - Cell Line, Tumor KW - Drug Resistance, Neoplasm KW - Dual Specificity Phosphatase 6 KW - physiology KW - Humans KW - Lung Neoplasms KW - drug therapy KW - Mitogen-Activated Protein Kinase Kinases KW - antagonists & inhibitors KW - Mitogen-Activated Protein Kinases KW - Oncogene Proteins, Fusion KW - analysis KW - Proto-Oncogene Proteins KW - genetics KW - Proto-Oncogene Proteins p21(ras) KW - Receptor Protein-Tyrosine Kinases KW - ras Proteins N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/nm.3930 ER -