TY - GEN AU - Di Paolo,Daniela AU - Yang,D AU - Pastorino,Fabio AU - Emionite,Laura AU - Cilli,Michele AU - Daga,Antonio AU - Destafanis,Elisa AU - Di Fiore,Annarita AU - Piaggio,Francesca AU - Brignole,Chiara AU - Xu,Xiaobao AU - Liang,Chris AU - Gibbons,James AU - Ponzoni,Mirco AU - Perri,Patrizia TI - New therapeutic strategies in neuroblastoma: combined targeting of a novel tyrosine kinase inhibitor and liposomal siRNAs against ALK SN - 1949-2553 PY - 2016///0810 KW - Anaplastic Lymphoma Kinase KW - Animals KW - Antineoplastic Agents KW - pharmacokinetics KW - Biological Availability KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Cell Survival KW - Combined Modality Therapy KW - Dose-Response Relationship, Drug KW - Female KW - Gene Expression Regulation, Enzymologic KW - Gene Expression Regulation, Neoplastic KW - Half-Life KW - Humans KW - Liposomes KW - Male KW - Mice, Inbred BALB C KW - Mice, Nude KW - Molecular Targeted Therapy KW - Mutation KW - Nanoparticles KW - Neuroblastoma KW - enzymology KW - Protein Kinase Inhibitors KW - RNA Interference KW - RNA, Small Interfering KW - genetics KW - RNAi Therapeutics KW - Receptor Protein-Tyrosine Kinases KW - antagonists & inhibitors KW - Signal Transduction KW - Transfection KW - Tumor Burden KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.18632/oncotarget.4342 ER -