TY - GEN AU - Tsou,Pei-Suen AU - Amin,M Asif AU - Campbell,Phillip L AU - Zakhem,George AU - Balogh,Beatrix AU - Edhayan,Gautam AU - Ohara,Ray A AU - Schiopu,Elena AU - Khanna,Dinesh AU - Koch,Alisa E AU - Fox,David A TI - Activation of the Thromboxane A2 Receptor by 8-Isoprostane Inhibits the Pro-Angiogenic Effect of Vascular Endothelial Growth Factor in Scleroderma SN - 1523-1747 PY - 2016///0301 KW - Adult KW - Collagen KW - Dinoprost KW - analogs & derivatives KW - Drug Combinations KW - Endothelial Cells KW - physiology KW - Female KW - Focal Adhesion Protein-Tyrosine Kinases KW - metabolism KW - Humans KW - Laminin KW - Male KW - Middle Aged KW - Neovascularization, Physiologic KW - Oxidative Stress KW - Phosphorylation KW - Proteoglycans KW - Receptors, Thromboxane A2, Prostaglandin H2 KW - drug effects KW - Scleroderma, Systemic KW - physiopathology KW - Vascular Endothelial Growth Factor A KW - antagonists & inhibitors KW - rho-Associated Kinases N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1038/jid.2015.323 ER -