TY  - GEN
AU  - Uckun,Fatih M
AU  - Myers,Dorothea E
AU  - Cheng,Jianjun
AU  - Qazi,Sanjive
TI  - Liposomal Nanoparticles of a Spleen Tyrosine Kinase P-Site Inhibitor Amplify the Potency of Low Dose Total Body Irradiation Against Aggressive B-Precursor Leukemia and Yield Superior Survival Outcomes in Mice
SN  - 2352-3964
PY  - 2016///0815
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Bone Marrow Transplantation
KW  - Cell Line, Tumor
KW  - Combined Modality Therapy
KW  - methods
KW  - Disease-Free Survival
KW  - Fusion Proteins, bcr-abl
KW  - genetics
KW  - Gene Expression
KW  - Humans
KW  - Intracellular Signaling Peptides and Proteins
KW  - antagonists & inhibitors
KW  - Liposomes
KW  - therapeutic use
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Inbred NOD
KW  - Mice, SCID
KW  - Mice, Transgenic
KW  - Nanoparticles
KW  - Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
KW  - mortality
KW  - Protein Kinase Inhibitors
KW  - Protein-Tyrosine Kinases
KW  - Radiation Tolerance
KW  - Radiation-Sensitizing Agents
KW  - Syk Kinase
KW  - Treatment Outcome
KW  - Whole-Body Irradiation
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1016/j.ebiom.2015.04.005
ER  -