Engel, Julian <br/><br/>
Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach.  [electronic resource] 

 -  Journal of medicinal chemistry  Sep 2015 
 - 6844-63 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.5b01082  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemistry<br/>Carcinoma, Non-Small-Cell Lung<br/>Cell Line, Tumor<br/>Cell Membrane Permeability<br/>Crystallography, X-Ray<br/>Databases, Chemical<br/>Drug Design<br/>Drug Resistance, Neoplasm<br/>ErbB Receptors--antagonists & inhibitors<br/>Humans<br/>Kinetics<br/>Lung Neoplasms<br/>Models, Molecular<br/>Molecular Conformation<br/>Mutation<br/>Pyrazoles--chemistry<br/>Pyrimidines--chemistry<br/>Quinazolines--chemistry<br/>Small Molecule Libraries<br/>Solubility<br/>Structure-Activity Relationship<br/>src-Family Kinases--chemistry