Cardoso, Juciane Lauren Cavalcanti

Impact of inhalational exposure to ethanol fuel on the pharmacokinetics of verapamil, ibuprofen and fluoxetine as in vivo probe drugs for CYP3A, CYP2C and CYP2D in rats. [electronic resource] - Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Oct 2015 - 99-105 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Validation Study

1873-6351

10.1016/j.fct.2015.08.002 doi


Air Pollutants, Occupational--toxicity
Animals
Aryl Hydrocarbon Hydroxylases--antagonists & inhibitors
Atmosphere Exposure Chambers
Biofuels--toxicity
Biomarkers--blood
Biotransformation--drug effects
Cytochrome P-450 CYP3A--chemistry
Cytochrome P-450 Enzyme Inducers--toxicity
Cytochrome P-450 Enzyme Inhibitors--blood
Cytochrome P-450 Enzyme System--chemistry
Enzyme Induction--drug effects
Ethanol--toxicity
Fluoxetine--blood
Ibuprofen--blood
Inhalation Exposure--adverse effects
Limonene Hydroxylases--antagonists & inhibitors
Male
Rats, Wistar
Toxicity Tests, Chronic--methods
Verapamil--analogs & derivatives