TY  - GEN
AU  - Akahane,K
AU  - Sanda,T
AU  - Mansour,M R
AU  - Radimerski,T
AU  - DeAngelo,D J
AU  - Weinstock,D M
AU  - Look,A T
TI  - HSP90 inhibition leads to degradation of the TYK2 kinase and apoptotic cell death in T-cell acute lymphoblastic leukemia
SN  - 1476-5551
PY  - 2016///0601
KW  - Apoptosis
KW  - drug effects
KW  - Apoptosis Regulatory Proteins
KW  - analysis
KW  - Bcl-2-Like Protein 11
KW  - Cell Line, Tumor
KW  - HSP90 Heat-Shock Proteins
KW  - antagonists & inhibitors
KW  - Humans
KW  - Isoxazoles
KW  - therapeutic use
KW  - Membrane Proteins
KW  - Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
KW  - drug therapy
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - Resorcinols
KW  - TYK2 Kinase
KW  - metabolism
KW  - bcl-Associated Death Protein
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/leu.2015.222
ER  -