Akahane, K <br/><br/>
HSP90 inhibition leads to degradation of the TYK2 kinase and apoptotic cell death in T-cell acute lymphoblastic leukemia.  [electronic resource] 

 -  Leukemia  Jan 2016 
 - 219-28 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1476-5551 
<br/><br/><label>Standard No.: </label>10.1038/leu.2015.222  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Apoptosis--drug effects<br/>Apoptosis Regulatory Proteins--analysis<br/>Bcl-2-Like Protein 11<br/>Cell Line, Tumor<br/>HSP90 Heat-Shock Proteins--antagonists & inhibitors<br/>Humans<br/>Isoxazoles--therapeutic use<br/>Membrane Proteins--analysis<br/>Precursor T-Cell Lymphoblastic Leukemia-Lymphoma--drug therapy<br/>Proto-Oncogene Proteins--analysis<br/>Proto-Oncogene Proteins c-bcl-2--analysis<br/>Resorcinols--therapeutic use<br/>TYK2 Kinase--metabolism<br/>bcl-Associated Death Protein--analysis