TY - GEN AU - Sarkar,Koustav AU - Sadhukhan,Sanjoy AU - Han,Seong-Su AU - Vyas,Yatin M TI - SUMOylation-disrupting WAS mutation converts WASp from a transcriptional activator to a repressor of NF-κB response genes in T cells SN - 1528-0020 PY - 2016///0106 KW - Adaptive Immunity KW - genetics KW - Blotting, Western KW - Cell Line KW - Electrophoretic Mobility Shift Assay KW - Flow Cytometry KW - Gene Expression Regulation KW - immunology KW - Humans KW - Immunoprecipitation KW - Mass Spectrometry KW - Mutagenesis, Site-Directed KW - Mutation KW - NF-kappa B KW - Polymerase Chain Reaction KW - Signal Transduction KW - Sumoylation KW - Th1 Cells KW - Transcriptional Activation KW - physiology KW - Transfection KW - Wiskott-Aldrich Syndrome Protein N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1182/blood-2015-05-646182 ER -