2,4-Diarylamino-pyrimidines as kinase inhibitors co-targeting IGF1R and EGFR(L⁸⁵⁸R/T⁷⁹⁰M). [electronic resource]
- Bioorganic & medicinal chemistry letters Oct 2015
- 4277-81 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3405
10.1016/j.bmcl.2015.07.089 doi
Antineoplastic Agents--chemical synthesis Cell Line, Tumor Cell Proliferation--drug effects Dose-Response Relationship, Drug Drug Screening Assays, Antitumor ErbB Receptors--antagonists & inhibitors Humans Models, Molecular Molecular Structure Protein Kinase Inhibitors--chemical synthesis Receptor, IGF Type 1 Receptors, Somatomedin--antagonists & inhibitors Structure-Activity Relationship