TY  - GEN
AU  - Marostica,Eleonora
AU  - Van Ammel,Karel
AU  - Teisman,Ard
AU  - Boussery,Koen
AU  - Van Bocxlaer,Jan
AU  - De Ridder,Filip
AU  - Gallacher,David
AU  - Vermeulen,An
TI  - Modelling of drug-induced QT-interval prolongation: estimation approaches and translational opportunities
SN  - 1573-8744
PY  - 2016///0810
KW  - Action Potentials
KW  - Animals
KW  - Anti-Bacterial Agents
KW  - blood
KW  - Bayes Theorem
KW  - Dogs
KW  - ERG1 Potassium Channel
KW  - Ether-A-Go-Go Potassium Channels
KW  - antagonists & inhibitors
KW  - Female
KW  - Fluoroquinolones
KW  - HEK293 Cells
KW  - Heart Conduction System
KW  - drug effects
KW  - Heart Rate
KW  - Humans
KW  - Models, Animal
KW  - Models, Cardiovascular
KW  - Models, Statistical
KW  - Moxifloxacin
KW  - Patch-Clamp Techniques
KW  - Potassium Channel Blockers
KW  - toxicity
KW  - Randomized Controlled Trials as Topic
KW  - Risk Assessment
KW  - Species Specificity
KW  - Torsades de Pointes
KW  - chemically induced
KW  - Toxicity Tests
KW  - Transfection
KW  - Translational Research, Biomedical
N1  - Publication Type: Comparative Study; Journal Article
UR  - https://doi.org/10.1007/s10928-015-9434-0
ER  -