Marostica, Eleonora <br/><br/>
Modelling of drug-induced QT-interval prolongation: estimation approaches and translational opportunities.  [electronic resource] 

 -  Journal of pharmacokinetics and pharmacodynamics  Dec 2015 
 - 659-79 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article 
<br/><br/><label>ISSN: </label>1573-8744 
<br/><br/><label>Standard No.: </label>10.1007/s10928-015-9434-0  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Action Potentials<br/>Animals<br/>Anti-Bacterial Agents--blood<br/>Bayes Theorem<br/>Dogs<br/>ERG1 Potassium Channel<br/>Ether-A-Go-Go Potassium Channels--antagonists & inhibitors<br/>Female<br/>Fluoroquinolones--blood<br/>HEK293 Cells<br/>Heart Conduction System--drug effects<br/>Heart Rate--drug effects<br/>Humans<br/>Models, Animal<br/>Models, Cardiovascular<br/>Models, Statistical<br/>Moxifloxacin<br/>Patch-Clamp Techniques<br/>Potassium Channel Blockers--toxicity<br/>Randomized Controlled Trials as Topic<br/>Risk Assessment<br/>Species Specificity<br/>Torsades de Pointes--chemically induced<br/>Toxicity Tests<br/>Transfection<br/>Translational Research, Biomedical