TY - GEN AU - Sette,G AU - Salvati,V AU - Mottolese,M AU - Visca,P AU - Gallo,E AU - Fecchi,K AU - Pilozzi,E AU - Duranti,E AU - Policicchio,E AU - Tartaglia,M AU - Milella,M AU - De Maria,R AU - Eramo,A TI - Tyr1068-phosphorylated epidermal growth factor receptor (EGFR) predicts cancer stem cell targeting by erlotinib in preclinical models of wild-type EGFR lung cancer SN - 2041-4889 PY - 2016///0412 KW - Adenocarcinoma KW - drug therapy KW - Aged KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - drug effects KW - Biomarkers, Pharmacological KW - metabolism KW - Carcinoma, Non-Small-Cell Lung KW - Carcinoma, Squamous Cell KW - Cell Line, Tumor KW - Drug Evaluation, Preclinical KW - ErbB Receptors KW - genetics KW - Erlotinib Hydrochloride KW - Female KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Lung Neoplasms KW - Male KW - Mice KW - Mice, SCID KW - Middle Aged KW - Neoplasm Staging KW - Neoplastic Stem Cells KW - Phosphorylation KW - Protein Kinase Inhibitors KW - Proto-Oncogene Proteins p21(ras) KW - Receptor, ErbB-2 KW - Signal Transduction KW - Tyrosine KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/cddis.2015.217 ER -