TY - GEN AU - Shi,Y AU - Ma,I T AU - Patel,R H AU - Shang,X AU - Chen,Z AU - Zhao,Y AU - Cheng,J AU - Fan,Y AU - Rojas,Y AU - Barbieri,E AU - Chen,Z AU - Yu,Y AU - Jin,J AU - Kim,E S AU - Shohet,J M AU - Vasudevan,S A AU - Yang,J TI - NSC-87877 inhibits DUSP26 function in neuroblastoma resulting in p53-mediated apoptosis SN - 2041-4889 PY - 2016///0412 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Brain Neoplasms KW - drug therapy KW - Caspase 3 KW - genetics KW - Cell Line, Tumor KW - Dual-Specificity Phosphatases KW - antagonists & inhibitors KW - Enzyme Inhibitors KW - Female KW - Gene Expression Regulation, Neoplastic KW - HSP27 Heat-Shock Proteins KW - Heat-Shock Proteins KW - Humans KW - Imidazoles KW - Intracellular Signaling Peptides and Proteins KW - Kidney KW - drug effects KW - Mice KW - Mice, Nude KW - Mitogen-Activated Protein Kinase Phosphatases KW - Molecular Chaperones KW - Neuroblastoma KW - Poly(ADP-ribose) Polymerases KW - Protein Serine-Threonine Kinases KW - Pyridines KW - Quinolines KW - RNA, Small Interfering KW - Signal Transduction KW - Tumor Suppressor Protein p53 KW - Xenograft Model Antitumor Assays KW - p38 Mitogen-Activated Protein Kinases N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/cddis.2015.207 ER -