TY  - GEN
AU  - Choi,Yong-Min
AU  - Kim,Han-Kyul
AU  - Shim,Wooyoung
AU  - Anwar,Muhammad Ayaz
AU  - Kwon,Ji-Woong
AU  - Kwon,Hyuk-Kwon
AU  - Kim,Hyung Joong
AU  - Jeong,Hyobin
AU  - Kim,Hwan Myung
AU  - Hwang,Daehee
AU  - Kim,Hyung Sik
AU  - Choi,Sangdun
TI  - Mechanism of Cisplatin-Induced Cytotoxicity Is Correlated to Impaired Metabolism Due to Mitochondrial ROS Generation
SN  - 1932-6203
PY  - 2016///0506
KW  - Acetylcysteine
KW  - pharmacology
KW  - Animals
KW  - Antineoplastic Agents
KW  - toxicity
KW  - Apoptosis
KW  - drug effects
KW  - Cell Line
KW  - Cell Proliferation
KW  - Cisplatin
KW  - Citric Acid Cycle
KW  - Dose-Response Relationship, Drug
KW  - Epithelial Cells
KW  - cytology
KW  - Gene Expression Regulation
KW  - Glycolysis
KW  - Humans
KW  - Injections, Intraperitoneal
KW  - Kidney Tubules
KW  - L-Lactate Dehydrogenase
KW  - genetics
KW  - Male
KW  - Membrane Potential, Mitochondrial
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Reactive Oxygen Species
KW  - agonists
KW  - Tumor Suppressor Protein p53
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0135083
ER  -