TY - GEN AU - Jayachandran,Devaraj AU - Laínez-Aguirre,José AU - Rundell,Ann AU - Vik,Terry AU - Hannemann,Robert AU - Reklaitis,Gintaras AU - Ramkrishna,Doraiswami TI - Model-Based Individualized Treatment of Chemotherapeutics: Bayesian Population Modeling and Dose Optimization SN - 1932-6203 PY - 2016///0506 KW - Antineoplastic Agents KW - administration & dosage KW - Bayes Theorem KW - Genetic Association Studies KW - Guanine Nucleotides KW - metabolism KW - Humans KW - Immunosuppressive Agents KW - Mercaptopurine KW - Models, Biological KW - Neoplasms KW - drug therapy KW - Precision Medicine KW - Prodrugs KW - Thionucleotides N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1371/journal.pone.0133244 ER -