TY  - GEN
AU  - Gray,Elizabeth E
AU  - Treuting,Piper M
AU  - Woodward,Joshua J
AU  - Stetson,Daniel B
TI  - Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome
SN  - 1550-6606
PY  - 2015///1215
KW  - Animals
KW  - Autoantibodies
KW  - blood
KW  - Autoimmune Diseases of the Nervous System
KW  - genetics
KW  - Cells, Cultured
KW  - Disease Models, Animal
KW  - Embryo, Mammalian
KW  - cytology
KW  - Exodeoxyribonucleases
KW  - Fibroblasts
KW  - drug effects
KW  - Gene Expression
KW  - Humans
KW  - Immunoblotting
KW  - Inflammation
KW  - Interferon-beta
KW  - Interferons
KW  - immunology
KW  - Macrophages
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Nervous System Malformations
KW  - Nucleotides, Cyclic
KW  - Nucleotidyltransferases
KW  - Phosphoproteins
KW  - Reverse Transcriptase Polymerase Chain Reaction
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.4049/jimmunol.1500969
ER  -