Grevengoed, Trisha J

Loss of long-chain acyl-CoA synthetase isoform 1 impairs cardiac autophagy and mitochondrial structure through mechanistic target of rapamycin complex 1 activation. [electronic resource] - FASEB journal : official publication of the Federation of American Societies for Experimental Biology Nov 2015 - 4641-53 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1530-6860

10.1096/fj.15-272732 doi


Animals
Autophagy--drug effects
Coenzyme A Ligases--deficiency
Mechanistic Target of Rapamycin Complex 1
Mice
Mice, Knockout
Mitochondria, Heart--genetics
Multiprotein Complexes--genetics
Myocardium--metabolism
Oxygen Consumption--drug effects
Proton-Translocating ATPases--metabolism
Sirolimus--pharmacology
TOR Serine-Threonine Kinases--genetics