Dijkgraaf, E M
A phase I trial combining carboplatin/doxorubicin with tocilizumab, an anti-IL-6R monoclonal antibody, and interferon-α2b in patients with recurrent epithelial ovarian cancer. [electronic resource]
- Annals of oncology : official journal of the European Society for Medical Oncology Oct 2015
- 2141-9 p. digital
Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
ISSN: 1569-8041
Standard No.: 10.1093/annonc/mdv309 doi
Subjects--Topical Terms: Adenocarcinoma, Clear Cell--blood Adenocarcinoma, Mucinous--blood Adult Aged Antibodies, Monoclonal, Humanized--administration & dosage Antineoplastic Combined Chemotherapy Protocols--therapeutic use Biomarkers, Tumor--blood CA-125 Antigen--blood Carboplatin--administration & dosage Cystadenocarcinoma, Serous--blood Dose-Response Relationship, Drug Doxorubicin--administration & dosage Endometrial Neoplasms--blood Enzyme-Linked Immunosorbent Assay Female Follow-Up Studies Humans Interferon alpha-2 Interferon-alpha--administration & dosage Interferon-gamma--blood Interleukin-6--blood Middle Aged Neoplasm Invasiveness Neoplasm Recurrence, Local--blood Neoplasm Staging Ovarian Neoplasms--blood Polyethylene Glycols--administration & dosage Prognosis Receptors, Interleukin-6--antagonists & inhibitors Recombinant Proteins--administration & dosage