Mohapatra, Purusottam

Resveratrol and curcumin synergistically induces apoptosis in cigarette smoke condensate transformed breast epithelial cells through a p21(Waf1/Cip1) mediated inhibition of Hh-Gli signaling. [electronic resource] - The international journal of biochemistry & cell biology Sep 2015 - 75-84 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1878-5875

10.1016/j.biocel.2015.07.009 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Breast Neoplasms--drug therapy
Cell Line
Cell Transformation, Neoplastic--drug effects
Curcumin--pharmacology
Cyclin-Dependent Kinase Inhibitor p21--genetics
Drug Synergism
Epithelial Cells--drug effects
Female
Hedgehog Proteins--metabolism
Humans
Immunoblotting
Mice, Inbred BALB C
Microscopy, Fluorescence
RNA Interference
Resveratrol
Signal Transduction--drug effects
Smoke
Stilbenes--pharmacology
Nicotiana--chemistry
Transcription Factors--genetics
Xenograft Model Antitumor Assays
Zinc Finger Protein GLI1
bcl-2-Associated X Protein--metabolism
bcl-X Protein--metabolism