TY - GEN AU - Kirane,Amanda AU - Ludwig,Kathleen F AU - Sorrelle,Noah AU - Haaland,Gry AU - Sandal,Tone AU - Ranaweera,Renate AU - Toombs,Jason E AU - Wang,Miao AU - Dineen,Sean P AU - Micklem,David AU - Dellinger,Michael T AU - Lorens,James B AU - Brekken,Rolf A TI - Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis SN - 1538-7445 PY - 2016///0104 KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - therapeutic use KW - Apoptosis KW - drug effects KW - Carcinoma, Pancreatic Ductal KW - drug therapy KW - Cell Division KW - Cell Line, Tumor KW - Cell Movement KW - Deoxycytidine KW - administration & dosage KW - Disease Progression KW - Drug Synergism KW - Epithelial-Mesenchymal Transition KW - Female KW - Gene Knockdown Techniques KW - Humans KW - Intercellular Signaling Peptides and Proteins KW - physiology KW - Mice KW - Mice, Inbred C57BL KW - Mice, Inbred NOD KW - Mice, SCID KW - Neoplasm Invasiveness KW - Neoplasm Metastasis KW - Neoplasm Proteins KW - antagonists & inhibitors KW - Pancreatic Neoplasms KW - Proto-Oncogene Proteins KW - RNA, Small Interfering KW - pharmacology KW - Receptor Protein-Tyrosine Kinases KW - Signal Transduction KW - Specific Pathogen-Free Organisms KW - Warfarin KW - Xenograft Model Antitumor Assays KW - Gemcitabine KW - Axl Receptor Tyrosine Kinase N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-14-2887-T ER -