Wagner, O F

Interaction between plasminogen activator inhibitor type 1 (PAI-1) bound to fibrin and either tissue-type plasminogen activator (t-PA) or urokinase-type plasminogen activator (u-PA). Binding of t-PA/PAI-1 complexes to fibrin mediated by both the finger and the kringle-2 domain of t-PA. [electronic resource] - The Journal of clinical investigation Aug 1989 - 647-55 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9738

10.1172/JCI114211 doi


Animals
Binding Sites
Blood Platelets--physiology
Fibrin--metabolism
Fibrinolysis
Glycoproteins--metabolism
Humans
Mice
Plasminogen Activators--metabolism
Plasminogen Inactivators
Tissue Plasminogen Activator--metabolism
Urokinase-Type Plasminogen Activator--metabolism